An open hole flute has holes at the center of the A, G, F, E, and D keys. Open holes are the standard among intermediate flutes and are the preference of the majority of flutists.

Playing open holes requires and therefore develops fingering accuracy that is not essential on plateau keys. Open holes can be used for effects such as bending and shading, and the player can crack some holes to bring the pitch back up when playing softly on high register notes. Some clever trills make use of the open hole venting for better pitch. All Azumi flutes have open holes.

Open holes can be closed with specially made plugs that can be inserted or removed by the player. Plugs are normally used during the adjustment period from a closed hole flute to an open hole flute. The plugs can be removed methodically, one at a time, until the technique and feel are developed. Most flutists take out the A first, then the F, and then the E. Lastly, remove the 3rd fingers, either the G or D first depending on the individual.